Evidence guide

Oral-Health Supplement Ingredients: Evidence Library

A growing evidence map for ingredients commonly used in oral-wellness supplements.

How we grade ingredient relevance

We look at the type of study, human versus laboratory evidence, dose, delivery method, outcome measured and whether findings are consistent across research.

Xylitol

One of the most studied sugar substitutes in dental contexts, with mixed evidence for caries prevention.

Cranberry

Polyphenols studied in oral-biofilm and adhesion models.

Grape-seed extract

Investigated in several dental applications, with calls for more human research.